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10.1016/j.ejphar.2009.08.022 80 SmirnovaO

Jakubowski H (2019) Homocysteine modification in protein structure/function and human disease

NOX2 serve as a mediator of oxidative stress, research findings demonstrated that A triggers oxidative stress via NOX2 activation, leading to the development of cerebral hypometabolism in murine models

This was similar to the effects of metformin on PCOS

Int J Pharm 446:1623

Additionally, the prodrug strategy should improve the pharmacokinetic properties of BSO, characterized as a free drug by short plasma half-life ( 95% purity